Morero oa Cleanroom o bua ka ho ntšoa ha lintho tse silafatsang tse kang li-microparticles, moea o kotsi, libaktheria, joalo-joalo moeeng ka har'a sebaka se itseng sa moea, le taolo ea mocheso oa ka tlung, bohloeki, khatello ea ka tlung, lebelo la phallo ea moea le kabo, ho sisinyeha ha lerata, mabone, motlakase o tsitsitseng, joalo-joalo ka har'a sebaka se itseng se hlokahalang. Re bitsa ts'ebetso e joalo ea tikoloho joalo ka morero oa kamore ea bohloeki. Morero o phethahetseng oa ho hloekisa o kenyelletsa likarolo tse ling tse robeli, ho kenyelletsa le likarolo tse robeli: mokhoa oa ho khabisa le oa tlhokomelo, tsamaiso ea HVAC, tsamaiso ea ventilation le exhaust, tsamaiso ea tšireletso ea mollo, tsamaiso ea motlakase, tsamaiso ea liphaephe, tsamaiso ea ho laola ka mokhoa o itekanetseng le tsamaiso ea metsi le metsi. Likarolo tsena hammoho li theha sistimi e felletseng ea projeke ea kamore ea bohloeki ho netefatsa ts'ebetso le phello ea eona.
1. Mokhoa oa Clenroom
(1). Mokhoa oa ho khabisa le oa tlhokomelo ea mohaho
Sehokelo sa mokhabiso le mokhabiso oa projeke ea kamore ea ho hloekisa hangata se kenyelletsa mokhabiso o ikhethileng oa sistimi ea mohaho o koaletsoeng joalo ka fatše, siling le karohano. Ka bokhutšoanyane, likarolo tsena li koahela libaka tse tšeletseng tsa sebaka se pota-potiloeng se nang le mahlakore a mararo, e leng holimo, lebota le fatše. Ho phaella moo, e boetse e kenyelletsa mamati, lifensetere le likarolo tse ling tse khabisitsoeng. Ho fapana le mokhabiso o tloaelehileng oa ntlo le mokhabiso oa indasteri, morero oa kamore ea ho hloekisa o ela hloko haholoanyane litekanyetso tse khethehileng tsa mokhabiso le lintlha ho netefatsa hore sebaka se kopana le litekanyetso tse khethehileng tsa bohloeki le bohloeki.
(2). Sistimi ea HVAC
E koahela setsi sa chiller (metsi a chesang) (ho kenyeletsoa pompo ea metsi, tora ea ho pholisa, joalo-joalo) le mochini oa phala ea moea o pholileng le lisebelisoa tse ling, liphaephe tsa moea o pholileng, lebokose la ho hloekisa moea (ho kenyeletsoa karolo ea phallo e tsoakiloeng, karolo ea phello ea mantlha, karolo ea ho futhumatsa, karolo ea sehatsetsi, karolo ea dehumidification, karolo ea khatello ea maikutlo, karolo ea phello e bohareng, karolo ea khatello ea maikutlo, joalo-joalo.)
(3). Sistimi ea moea le ea ho tsoa
Sistimi ea ventilation ke sete e felletseng ea lisebelisoa tse nang le mochini o kenang ka har'a moea, mochini oa ho tsoa, mochini oa phepelo ea moea, fan, lisebelisoa tsa ho futhumatsa le ho futhumatsa, sefahla, sistimi ea taolo le lisebelisoa tse ling tse thusang. Sistimi ea ho tima ke sistimi e felletseng e nang le hood kapa moea o kenang, lisebelisoa tsa kamore e hloekileng le fan.
(4). Sistimi ea ts'ireletso ea mollo
Tsela ea maemo a tšohanyetso, mabone a tšohanyetso, sefafatsi, setima-mollo, hose ea mollo, lisebelisoa tsa alamo tse itšebetsang, shutter e thibelang mollo, joalo-joalo.
(5). Sistimi ea motlakase
E kenyelletsa likarolo tse tharo: mabone, matla le matla a fokolang, ka ho khetheha a koahela mabone a tlhoekiso, li-sockets, lik'habote tsa motlakase, mela, ho shebella le thelefono le mekhoa e meng e matla le e fokolang ea hona joale.
(6). Sistimi ea liphaephe tsa ts'ebetso
Morerong oa kamore ea bohloeki, e kenyelletsa haholo: liphaephe tsa khase, liphaephe tsa thepa, lipeipi tsa metsi a hloekisitsoeng, lipeipi tsa metsi a enteng, mouoane, liphaephe tse hloekileng tsa mouoane, liphaephe tsa metsi tsa mantlha, liphaephe tsa metsi tse potolohang, liphaephe tsa metsi, liphaephe tsa metsi, condensate, lipeipi tsa metsi a pholileng, jj.
(7). Mokhoa oa ho laola o iketsang
Ho kenyelletsa taolo ea mocheso, taolo ea mocheso, bophahamo ba moea le taolo ea khatello, tatellano ea ho bula le taolo ea nako, joalo-joalo.
(8). Sistimi ea phepelo ea metsi le drainage
Sebopeho sa sistimi, khetho ea liphaephe, ho beha liphaephe, lisebelisoa tsa drainage le sebopeho se senyenyane sa drainage, sistimi ea phallo ea phaposi e hloekileng, litekanyo tsena, moralo oa tsamaiso ea drainage le ho kenya, jj.
Indasteri ea lijo, seteishene sa tlhahlobo ea boleng, indasteri ea lisebelisoa tsa elektroniki, sepetlele, indasteri ea tlhokomelo ea bongaka, sefofane, litsi tsa lipatlisiso tsa mahlale, lifeme tsa meriana, li-microelectronics, kamore e hloekileng ea baeloji le liindasteri tse ling li fana ka mefuta e fapaneng le maemo a bohloeki ba sehlopha sa 100000 sa lithupelo tse hloekileng le moralo oa sistimi e hloekisang moea, ho kenya le ho aha, ho laela, ts'ebeletso ea kamora ho rekisa le litharollo tse ling ka kakaretso. Laeborari ea biosafety e entsoeng ke k'hamphani ea rona e netefatsa boleng ba kaho mme e fihlela litlhoko tsa litekanyetso tse akaretsang tsa moaho.
2. Litlhoko tsa tšebeletso ea kamoreng ea bohloeki
(1). Litšebeletso tsa kamore ea ho hloekisa
① Rala le ho nchafatsa liphaposi tse hloekileng tse nang le moea o hloekisitsoeng le lilaboratori tse hloekileng, tse se nang lerole le tse hloekileng tsa maemo a fapaneng a tlhoekiso, litlhoko tsa tšebetso le merero ea fatše.
② Nchafatsa likamore tse hloekileng tse nang le litlhoko tse khethehileng tse kang khatello e mpe e amanang le mocheso, mocheso o phahameng, thibelo ea mollo le ho phatloha, ho koala molumo le ho khutsisa, ho thibela likokoana-hloko, ho tlosa chefo le ho ntša monko o monate, le anti-static.
③ Haha mabone, lisebelisoa tsa motlakase, matla, litsamaiso tsa taolo ea motlakase le litsamaiso tsa taolo ea moea o ikemetseng tse tsamaellanang le phaposi e hloekileng.
3. Lisebelisoa tsa kamore ea ho hloekisa
(1). Likamore tse hloekileng tsa lipetlele
Likamore tse hloekileng tsa lipetlele li kenyelletsa likamore tse hloekileng tsa ho buoa le liwote tse hloekileng. Liwate tse hloekileng tsa lipetlele haholo-holo ke libaka tseo li-fungus li laoloang ka thata ho thibela bakuli ho tšoaetsoa kapa ho baka liphello tse tebileng.
(2). Lilaboratori tsa letoto la P-level
① Lilaboratori tsa P3 ke lilaboratori tsa boemo ba 3 ba biosafety. Lilaboratori tsa Biosafety li arotsoe ka mekhahlelo e mene ho latela tekanyo ea kotsi ea likokoana-hloko le chefo ea tsona, 'me boemo ba 1 bo le tlase le boemo ba 4 bo phahameng. Li arotsoe ka mekhahlelo e 'meli: boemo ba lisele le boemo ba liphoofolo, 'me boemo ba liphoofolo bo aroloa hape ka boemo ba liphoofolo tse nyenyane le boemo bo boholo ba liphoofolo. Laeborari ea pele ea P3 naheng ea heso e hahiloe ka 1987 'me e ne e sebelisetsoa haholo lipatlisiso tsa AIDS.
②P4 e bua ka laboratori ea boemo ba 4 ba biosafety, e sebelisoang ka ho khetheha bakeng sa lipatlisiso tsa mafu a tšoaetsanoang haholo. Ke boemo bo phahameng ka ho fetisisa ba laboratori ea biosafety lefatšeng. Ha ho na laboratori e joalo Chaena hajoale. Ho latela litsebi tse amehang, mehato ea polokeho ea lilaboratori tsa P4 e thata ho feta ea lilaboratori tsa P3. Bafuputsi ha baa lokela ho apara liaparo tse sireletsang ka ho feletseng feela empa hape ba nke li-cylinders tsa oksijene ha ba kena.
(3). Boenjiniere ba likamore tse hloekileng tsa lifeme le lithupelo
Mekhoa ea kaho e ka aroloa ka boenjiniere ba sechaba le mefuta e hlophisitsoeng.
The prefabricated hloekile workshop tsamaiso ea haholo-holo e entsoe ka tsamaiso ea moea conditioning phepelo, tsamaiso ea moea khutlela, khutlela moea, exhaust yuniti, sebopeho se koaletsoeng, batho le lintho tse bonahalang diyuniti hloekileng, ka sehloohong, bohareng le boemong bo phahameng filtration moea, tsamaiso ea khase le metsi, matla le mabone, ho sebetsa tikolohong ea ho sebetsa parameter leihlo le alamo, tshireletso ea mollo, puisano le anti-static kalafo fatše.
①GMP mekhoa ea tlhoekiso ea lithupelo tse hloekileng:
Linako tsa phetoho ea moea: sehlopha sa 100000 ≥15 linako; sehlopha sa 10000 ≥20 linako; sehlopha sa 1000 ≥30 linako tse ling.
Phapang ea khatello: workshop e kholo ho kamoreng e haufi ≥5Pa;
Karolelano ea lebelo la moea: sehlopha sa 100 se hloekileng sa workshop 03-0.5m / s;
Mocheso:> 16 ℃ mariha; <26℃ lehlabula; feto-fetoha ±2℃. Mongobo 45-65%; mongobo ka har'a workshop e hloekileng ea GMP ka ho khetheha o ka ba 50%; mongobo ka har'a workshop ea elektroniki o phahame hanyane ho qoba motlakase o sa fetoheng. Lerata ≤65dB(A); tlatsetso ea moea o hloekileng ke 10% -30% ea kakaretso ea phepelo ea moea; khanya: 300LX.
②GMP lisebelisoa tsa sebopeho sa workshop:
Mabota le liphanele tsa siling tsa workshop e hloekileng hangata li entsoe ka lipoleiti tsa tšepe tsa 'mala oa sandwich tse 50mm, tse ntle le tse thata. mamati a sekhutlo sa Arc, liforeimi tsa lifensetere, joalo-joalo hangata li entsoe ka li-profiles tse khethehileng tsa anodized aluminium;
Mokatong o ka etsoa ka epoxy self-leveling floor kapa high-grade wear-resistant plastic floor. Haeba ho na le tlhokahalo ea anti-static, mofuta oa anti-static o ka khethoa;
Phepelo ea moea le li-ducts tsa ho khutlisa li entsoe ka lakane e chesitsoeng e chesang, 'me letlapa la polasetiki le nang le lelakabe la PF le sa sebetseng le nang le tlhoekiso e ntle le ts'ebetso ea ho boloka mocheso;
Lebokose la hepa le sebelisa foreime ea tšepe e sa hloekang, e ntle ebile e hloekile, 'me poleiti ea letlooeng e nang le libotlolo e sebelisa poleiti ea aluminium e pentiloeng, e thibelang mafome le lerōle le bonolo ho e hloekisa.
(4). Boenjiniere ba kamore ea ho hloekisa ea elektronike le ea 'mele
Ka kakaretso e sebetsa ho lisebelisoa tsa elektroniki, likamore tsa likhomphutha, lifeme tsa semiconductor, indasteri ea likoloi, indasteri ea sefofane, photolithography, tlhahiso ea li-microcomputer le liindasteri tse ling. Ntle le bohloeki ba moea, ho boetse hoa hlokahala ho netefatsa hore litlhoko tsa anti-static lia finyelloa.
Nako ea poso: Feb-28-2025